Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system.
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA. dunnickj@niehs.nih.gov Abstract Ma Huang (equivalent to 0, 12.5, 25, or 50 mg/kg ephedrine) or ephedrine (0, 6.25, 12.5, 25 mg/kg) were administered as one bolus oral dose to male F344 rats with and without caffeine. The herbal medicine Ma Huang (ephedra) in combination with caffeine caused rapid clinical signs of toxicity including salivation, hyperactivity, ataxia, and ev
Electrocoating of stainless steel coronary stents for extended release of paclitaxel
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel Department of Inorganic and Analytical Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel Expert in Toxicologic Pathology, Sackler School of Medicine, Tel Aviv University, Timrat 36576, Israel AQ2 National Institute for Pharmaceutical Research (NIPER), New Delhi, India Abstract: Nonbiodegradable polyme